Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR

NANot yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

August 30, 2024

Study Completion Date

January 31, 2025

Conditions
Pain, PostoperativePeriapical; Infection
Interventions
COMBINATION_PRODUCT

Zinc oxide propolis

"Propolis liquid (Brazilian Green Bee Propolis Liquid Extract, Uniflora®) and Zinc oxide powder will be mixed on a glass slab with the help of a stainless -steel spatula.~• The mixing ratio of zinc oxide powder and Propolis liquid is 2:1 until a paste like consistency is reached."

COMBINATION_PRODUCT

Modified triple antibiotic paste

"Chemotherapeutic agents used are metronidazole tablets 500 mg (Flagyl®, Sanofi, Egypt), ciprofloxacin tablets 500 mg (Ciprofloxacin tablets USP 39®, European pharmaceuticals, Egypt,), and clindamycin capsules 300 mg(Dalacin C™ Pfizer, Egypt).~* After the removal of enteric coating of tablets with the help of blade, the drugs are pulverized into fine powder using sterilized mortar and pestle.~* The same amount of each powdered drug (1:1:1) is mixed to form m-TAP powder which is mixed with one part of propylene glycol (P) and the same volume of macrogol (M) to form a paste like consistency"

All Listed Sponsors
lead

Cairo University

OTHER

NCT06158451 - Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR | Biotech Hunter | Biotech Hunter