ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

October 3, 2024

Primary Completion Date

May 20, 2025

Study Completion Date

May 20, 2025

Conditions
Adverse Effect
Interventions
DRUG

Norepinephrine

An initial infusion dose of prophylactic norepinephrine (0.05 ug/kg/min) simultaneous with spinal anesthesia. The dose administered to subsequent patients varied by increments or decrements of 0.01 ug/kg/min of prophylactic norepinephrine according to the responses of previous patients according to the up-down sequential allocation.

DRUG

Phenylephrine

An initial infusion dose of prophylactic phenylephrine (0.5 ug/kg/min) simultaneous with spinal anesthesia. The dose administered to subsequent patients varied by increments or decrements of 0.1 ug/kg/min of prophylactic phenylephrine according to the responses of previous patients according to the up-down sequential allocation.

Trial Locations (1)

750004

General hospital of Ningxia University, Yinchuan

All Listed Sponsors
lead

General Hospital of Ningxia Medical University

OTHER

NCT06158022 - ED90 of Norepinephrine and Phenylephrine Infusions in Preeclamptic Patients | Biotech Hunter | Biotech Hunter