Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer

NAActive, not recruitingINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

April 1, 2027

Study Completion Date

April 1, 2029

Conditions
Stage II-III Gastric Cancer
Interventions
DRUG

MRD-guided therapy

MRD negative stage II gastric cancer: Observation; MRD negative stage III gastric cancer: S1 (40-60 mg, PO, bid, d1-d14 q3w); MRD positive stage II/III gastric cancer: XELOX (Oxaliplatin 130mg/m2, d1 +Capecitabine 1000mg/m2,PO. bid, d1-14, q3w) or SOX (Oxaliplatin 130mg/m2, d1 +S-1 40-60 mg, PO. bid, d1-14, q3w); MRD-negative patients will receive XELOX or SOX if MRD becomes positive.

Trial Locations (5)

250012

Qilu Hospital of Shandong Univertisy, Jinan

Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan

264000

Yantai Yuhuangding Hospital, Yantai

266000

The Affiliated Hospital of Qingdao University, Qingdao

Unknown

Jinan Central Hospital, Jinan

All Listed Sponsors
collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

Jinan Central Hospital

OTHER

collaborator

Yantai Yuhuangding Hospital

OTHER

collaborator

The Affiliated Hospital of Qingdao University

OTHER

lead

Qilu Hospital of Shandong University

OTHER

NCT06157216 - Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer | Biotech Hunter | Biotech Hunter