NCT06153966 - PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717 | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 4, 2024

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2027

Conditions

Prion Disease

Interventions

DRUG

ION717

ION717 will be administered by IT injection.

DRUG

Placebo

Placebo-matching ION717 will be administered by IT injection.

Trial Locations (16)

3050

Royal Melbourne Hospital, Parkville

10016

NYU Langone Health, New York

20133

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan

37075

University Medical Center Göttingen, Göttingen

44106

University Hospitals Cleveland Medical Center, Cleveland

75013

Hôpital Universitaire Pitié Salpêtrière, Paris

80204

University of Colorado Hospital, Denver

90095

UCLA Neurology Clinic, Los Angeles

6423906

Tel Aviv Sourasky Medical Center, Tel Aviv

02114

Massachusetts General Hospital, Boston

T6G 2M8

University of Alberta, Edmonton

H3A 2B4

McGill University Health Centre, Montreal

372-0006

Mihara Memorial Hospital, Gunma

187-8551

National Center of Neurology and Psychiatry, Tokyo

751-0826

Neuromuscular Center Yoshimizu Hospital, Yamaguchi

08036

Hospital Clinic De Barcelona, Barcelona