NCT06150560View on ClinicalTrials.gov

A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)

PHASE3RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

June 1, 2028

Study Completion Date

June 1, 2028

Conditions
Coarctation of AortaHigh Blood Pressure
Interventions
DRUG

Losartan

50mg administered orally once daily for 52 weeks.

DRUG

Amlodipine

5mg Amlodipine administered orally once daily for 52 weeks.

DRUG

Placebo

Oral capsules that contain no active drug ingredients administered orally once daily for 52 weeks.

Trial Locations (1)

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

Sponsors

Lead Sponsor

Mayo Clinic
All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Mayo Clinic

OTHER

NCT06150560 - A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) | Biotech Hunter | Biotech Hunter