Combination of Cadonilimab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-006)

Patients received cadonilimab 10 mg/kg every 3 weeks for up to 16 cycles.

Patients received 2 cycles of induction chemotherapy with paclitaxel/cisplatin (paclitaxel 135 mg/m2 and cisplatin 75 mg/m2) prior to radiotherapy. Then patients will not receive chemotherapy during radiotherapy.

All patients received external-beam radiation using intensity-modulated radiotherapy. The prescribed dose is 50.4 Gy in 28 fractions over 5-6 weeks.