A Study of HAIC Combined With Lenvatinib and Envolizumab in Potentially Resectable Hepatocellular Carcinoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

December 15, 2023

Primary Completion Date

March 3, 2025

Study Completion Date

December 31, 2026

Conditions
Potentially Resectable Hepatocellular Carcinoma
Interventions
DRUG

FOLFOX-HAIC+Lenvatinib+Envolizumab

"FOLFOX-HAIC: Oxaliplatin 130 or 85 mg/m2; leucovorin 200 mg/m2; fluorouracil 400 mg/m2 intravenous bolus followed by fluorouracil 2400 mg/m2 continuous infusion over 23 hours, Q3W, 2 to 4 cycles;~Lenvatinib: 8 mg/day (BW \< 60 kg) or 12 mg/day (BW ≥ 60 kg), PO, 3-4 cycles;~Envolizumab: 300 mg, SC, Q3W, 3-4 cycles."

All Listed Sponsors
lead

Sun Yat-sen University

OTHER