Neuronostatin - a Glucagonotropic Agent in Humans?

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

December 6, 2022

Primary Completion Date

September 25, 2024

Study Completion Date

September 25, 2024

Conditions
Type 1 DiabetesHypoglycemiaType1diabetes
Interventions
OTHER

Infusion of either NST or placebo at different blood glucose levels

In a randomized, double-blind crossover design, participants will undergo six experimental days with controlled plasma glucose levels, consisting of two euglycemic, two hyperglycemic (around 8mmol/l), and two hypoglycemic (around 2.5mmol/l) days, with each pair of similar days involving the administration of either saline (placebo) or NST.

Trial Locations (1)

2900

Center for Clinical Metabolic Research, Gentofte Hospital, Hellerup

All Listed Sponsors
collaborator

The Novo Nordisk Foundation Center for Basic Metabolic Research

OTHER

lead

University Hospital, Gentofte, Copenhagen

OTHER