21
Participants
Start Date
January 13, 2024
Primary Completion Date
June 30, 2025
Study Completion Date
December 30, 2025
individualized mRNA neoantigen vaccine (mRNA-0523-L001)
Individualized mRNA neoantigen vaccine (mRNA-0523-L001) will be injected intramuscularly every 21 days for 9 cycles. Dose escalation will be administered in 3 patients. 18 additional patients will be recruited and administered at the maximum tolerated(MTD) dose for all nine cycles.
RECRUITING
Ruijin hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai
Shanghai Jiao Tong University School of Medicine
OTHER