Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments

RecruitingOBSERVATIONAL
Enrollment

180

Participants

Timeline

Start Date

March 5, 2024

Primary Completion Date

January 1, 2026

Study Completion Date

July 1, 2026

Conditions
Bladder CancerMetastatic Bladder CancerUnresectable Bladder CarcinomaUrothelial Carcinoma
Interventions
BEHAVIORAL

Geriatric-8 Survey

A screening tool to evaluate frailty and at-risk participants by covering multiple domains that contribute to frailty, including mobility, functional status, pharmacologic burden, and underlying psychologic burden. A total score ranges from 0 to 17 with participants scoring \> 14 points are more likely to be fit, or having a better health status, while those scoring 0 - 14 would benefit from further comprehensive geriatric assessment.

BEHAVIORAL

National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy Bladder Symptom Index-18 (FBISI-18)

Patient reported, sixteen question survey focused on evaluation of quality of life in patients with bladder cancer.

BEHAVIORAL

Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE®)

Patient-reported questionnaire that evaluates cancer-specific toxicity, developed based upon Common Terminology Criteria for Adverse Events.

Trial Locations (1)

02215

RECRUITING

Dana-Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Comprehensive Cancer Network

NETWORK

collaborator

EMD Serono

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER

NCT06138561 - Management of Cisplatin-Ineligible Patients With Metastatic Bladder Cancer and The Role of Geriatric Assessments | Biotech Hunter | Biotech Hunter