First-In-Human Study of Bispecific Antibody MR001 In Subjects With Advanced Solid Tumors

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

November 30, 2023

Primary Completion Date

July 31, 2026

Study Completion Date

October 31, 2026

Conditions
Advanced Solid Tumors
Interventions
DRUG

MR001

"Dose Level 1: 0.5 mg/kg Intravenously (IV) Frequency: administered on Day 1 of each cycle (every 3 weeks), 1 cycle~Dose Level 2: 2 mg/kg Intravenously (IV) Frequency: administered on Day 1 of each cycle (every 3 weeks), 4 cycle~Dose Level 3: 6 mg/kg Intravenously (IV) Frequency: administered on Day 1 of each cycle (every 3 weeks), 4 cycle~Dose Level 4: 10 mg/kg Intravenously (IV) Frequency: administered on Day 1 of each cycle (every 3 weeks), 4 cycle~Dose Level 5: 15 mg/kg Intravenously (IV) Frequency: administered on Day 1 of each cycle (every 3 weeks), 4 cycle~Dose Level 6: 20 mg/kg Intravenously (IV) Frequency: administered on Day 1 of each cycle (every 3 weeks), 4 cycle"

Trial Locations (1)

510-515

Nanfang Hospital, Southern Medical University, Guangzhou

All Listed Sponsors
lead

Nanfang Hospital, Southern Medical University

OTHER

NCT06134531 - First-In-Human Study of Bispecific Antibody MR001 In Subjects With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter