Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC

PHASE2RecruitingINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

April 2, 2024

Primary Completion Date

April 2, 2026

Study Completion Date

April 2, 2028

Conditions
Non-small Cell Lung Cancer
Interventions
DRUG

Toripalimab

Toripalimab treatment (240mg intravenously every 3 weeks) started on day 3 after cryoablation, until occurrence of termination event specified in the protocol.

OTHER

Cryoablation

The ablation was performed on the first day of each cycle, and the target lesions were comprehensively screened for cryoablation based on the location and size of the lesions.

Trial Locations (3)

200000

RECRUITING

Shanghai Chest Hospital, Shanghai

Unknown

NOT_YET_RECRUITING

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

NOT_YET_RECRUITING

Zhongshan Hospital, Fudan University, Shanghai

All Listed Sponsors
lead

Shanghai Chest Hospital

OTHER