Safety and Immunogenicity of Ervebo® and Zabdeno® Booster Vaccines Against Ebola Virus Following Previous Vaccination with the Zabdeno/Mvabea® or Ervebo® Vaccine Schedules in DRC

PHASE3RecruitingINTERVENTIONAL

Enrollment

624

Participants

Timeline

Start Date

February 25, 2025

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2026

Conditions

Ebola Virus Disease

Interventions

DRUG

Zabdeno® booster

A single Zabdeno® booster vaccination

DRUG

Ervebo® booster

A single Ervebo® booster vaccination

Trial Locations (2)

NOT_YET_RECRUITING

Institut National de Recherche Biomédicale (INRB), Goma

RECRUITING

Institut National de Recherche Biomédicale (INRB), Kinshasa

All Listed Sponsors

collaborator

Institut National pour la Recherche Biomedicale (INRB)

UNKNOWN

lead

Institute of Tropical Medicine, Belgium

OTHER