NCT06126614View on ClinicalTrials.gov

Infection Prophylaxis in Total Joint Replacement

PHASE3RecruitingINTERVENTIONAL
Enrollment

21,006

Participants

Timeline

Start Date

May 7, 2024

Primary Completion Date

November 30, 2028

Study Completion Date

November 30, 2028

Conditions
Periprosthetic Joint Infection
Interventions
DRUG

Chlorhexidine Gluconate

0.05% chlorhexidine gluconate solution for irrigation

DRUG

Vancomycin Hydrochloride

2 grams of topical vancomycin hydrochloride added to the wound

OTHER

Povidone-Iodine

0.35% povidone-iodine solution for irrigation

OTHER

Saline

saline for irrigation

Trial Locations (1)

L8V 1C3

RECRUITING

Hamilton Health Sciences - Juravinski Hospital and Cancer Centre, Hamilton

All Listed Sponsors
collaborator

McMaster University

OTHER

collaborator

Ontario Clinical Oncology Group (OCOG)

OTHER

lead

Hamilton Health Sciences Corporation

OTHER