Incidence and Clinical Impact of Serum Hyperamylasemia (POH) After Pancreatectomy on Postoperative Outcome and Patient Safety

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

July 18, 2023

Primary Completion Date

January 31, 2026

Study Completion Date

April 30, 2026

Conditions
PancreatectomyHyperamylasemiaPancreatitis, Acute
Interventions
OTHER

Pancreatectomy

"Patients who underwent pancreatectomy will be enrolled. Serum amylase and lipase will be measured preoperatively. During surgery, blood samples will be taken after completing the pancreatic anastomosis and at the end of the operation during skin suture. Patients will be followed up during hospital stay, 3 and 6 months after discharge. The clinical outcome (complications, rescue pancreatectomy) will be recorded and analysed.~Postoperative blood samples, according to clinical standard, will be taken at the 1, 2, 3, 5 and 7 day postoperatively. In addition to amylase several more parameters will be examined intra- and postoperatively: leucocytes, lipase, CRP, bilirubin, transaminases, AP, GGT, creatinine, interleukin-6, PCT. Intraoperative 1-2ml of pancreas juice will be taken for the evaluation of amylase and lipase levels."

Trial Locations (1)

01307

RECRUITING

University Hospital Dresden, Dept. Visceral, Thoracic and Vascular Surgery, Dresden

All Listed Sponsors
lead

Technische Universität Dresden

OTHER