51
Participants
Start Date
October 30, 2023
Primary Completion Date
July 31, 2026
Study Completion Date
December 31, 2026
Adebelizumab+Carboplatin+Etoposide+Concurrent Radiotherapy
Eligible patients will receive the following treatment schemes: adebelizumab+carboplatin+etoposide, with one treatment cycle every three weeks. After 4-6 cycles, adebelizumab maintenance therapy combined with concurrent radiotherapy will be given, and conventional radiotherapy will be given to chest lesions (2Gy\*(20-30)f), brain (3Gy\*10f)/ bone (3Gy\*10f)/ adrenal gland. Immunotherapy is suspended during radiotherapy for chest lesions and lymph nodes in mediastinum, and immunotherapy is given 1-2 weeks after radiotherapy. Radiotherapy for other metastatic lesions can be carried out simultaneously with immunotherapy.
RECRUITING
The First Affiliated Hospital of Shandong First Medical University, Jinan
Qianfoshan Hospital
OTHER