Efficacy of a Probiotic and Microbiological Analysis on Oral Complications in Patients With HNC

NACompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

October 3, 2022

Primary Completion Date

December 20, 2024

Study Completion Date

December 20, 2024

Conditions
Quality of LifeOral MucositisDental PlaquePeriodontal DiseasesXerostomiaDysbiosis
Interventions
DIETARY_SUPPLEMENT

The probiotic to be used in the intervention corresponds to PRODEFEN Plus manufactured by ITALFARMACO S.A. laboratory

Each patient should take 1 sachet per day, dissolve it in a glass of water, hold in the mouth for 2-3 minutes and then swallow, for a period of 30 days.

OTHER

Placebo

The placebo will be administered in an envelope with the same packaging, size, shape and color of contents as the intervention of interest, except that the placebo will not contain the active ingredient of the intervention.

Trial Locations (1)

08907

University of Barcelona, Barcelona

All Listed Sponsors
lead

University of Barcelona

OTHER