62
Participants
Start Date
October 3, 2022
Primary Completion Date
December 20, 2024
Study Completion Date
December 20, 2024
The probiotic to be used in the intervention corresponds to PRODEFEN Plus manufactured by ITALFARMACO S.A. laboratory
Each patient should take 1 sachet per day, dissolve it in a glass of water, hold in the mouth for 2-3 minutes and then swallow, for a period of 30 days.
Placebo
The placebo will be administered in an envelope with the same packaging, size, shape and color of contents as the intervention of interest, except that the placebo will not contain the active ingredient of the intervention.
University of Barcelona, Barcelona
University of Barcelona
OTHER