First Line Treatment With Olaparib in Combination With Bevacizumab in HRD Positive Patients

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

September 15, 2023

Primary Completion Date

March 15, 2027

Study Completion Date

September 15, 2027

Conditions
Carcinoma, Ovarian Epithelial
Interventions
DRUG

Olaparib

Olaparib is considered the study treatment. Olaparib tablets will be taken at the dose of 300 mg (2 x 150 mg tablet) twice daily adding to bevacizumab at a dose of 15 mg per kilogram of body weight every 3 weeks

DRUG

Bevacizumab

Bevacizumab will be taken at a dose of 15 mg per kilogram of body weight every 3 weeks

Trial Locations (2)

22042

Azienda Socio Sanitaria Territoriale (ASST) Lariana, San Fermo della Battaglia

35128

Istituto Oncologico Veneto IRCCS, Padua

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Mario Negri Institute for Pharmacological Research

OTHER