An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

RecruitingOBSERVATIONAL
Enrollment

300

Participants

Timeline

Start Date

November 27, 2023

Primary Completion Date

November 27, 2026

Study Completion Date

February 1, 2027

Conditions
Unresectable Hepatocellular Carcinoma
Interventions
DRUG

Atezolizumab

Atezolizumab combined with Bevacizumab, immune checkpoint inhibitors combination.

DRUG

Bevacizumab

Atezolizumab combined with Bevacizumab, immune checkpoint inhibitors combination.

DRUG

Durvalumab

Durvalumab combined with Tremelimumab, another immuno-oncology (IO) checkpoint inhibitors combination.

DRUG

Tremelimumab,

Durvalumab combined with Tremelimumab, another immuno-oncology (IO) checkpoint inhibitors combination.

Trial Locations (20)

14203

NOT_YET_RECRUITING

Roswell Park Comprehensive Cancer Center, Buffalo

19104

NOT_YET_RECRUITING

Corporal Michael J Crescenz Department Of Veterans Affairs Medical Center, Philadelphia

19141

NOT_YET_RECRUITING

Einstein Medical Center, Philadelphia

21202

NOT_YET_RECRUITING

Mercy Medical Center - Medline Healthcare Services LLC, Baltimore

45219

NOT_YET_RECRUITING

University Of Cincinnati Division Of Hematology Oncology - UC Health System, Cincinnati

48109

NOT_YET_RECRUITING

University of Michigan Health System, Ann Arbor

Unknown

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

WITHDRAWN

Many Locations, Multiple Locations

NOT_YET_RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

RECRUITING

Many Locations, Multiple Locations

WITHDRAWN

Many Locations, Multiple Locations

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY

NCT06117891 - An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery | Biotech Hunter | Biotech Hunter