NCT06114667View on ClinicalTrials.gov

Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis

NANot yet recruitingINTERVENTIONAL
Enrollment

174

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

November 1, 2028

Study Completion Date

November 1, 2028

Conditions
Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseHypercapnic AcidosisRespiratory Failure With Hypercapnia
Interventions
DEVICE

Ventilatory support via nasal high flow

Ventilatory support will be applied in 2h sessions and resumed as needed according to international guidelines for NIV treatment.

DEVICE

Ventilatory support via NIV

Ventilatory support will be applied in 2h sessions and resumed as needed according to international guidelines for NIV treatment.

Trial Locations (3)

Unknown

Centre hospitalier universitaire de Montpellier, Montpellier

Centre hospitalier universitaire de Nimes, Nîmes

Centre Hospitalier Universitaire de Poitiers, Poitiers

All Listed Sponsors
collaborator

Fisher and Paykel Healthcare

INDUSTRY

lead

University Hospital, Montpellier

OTHER

NCT06114667 - Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis | Biotech Hunter | Biotech Hunter