Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

NARecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Mild Traumatic Brain InjuryPhotophobia
Interventions
DEVICE

Micro Current Neurofeedback Device using Low-Frequency Pulse-Based Transcranial Electrical Stimulation

The EEG interface device is a J\&J Engineering 1-330 C2 box. The software used to determine LIP-tES feedback patterns was developed by Neurogen High Performance Neurofeedback. The EEG sampling frequency is 256 Hz on each of 2 EEG acquisition channels. The feedback LIP-tES is delivered via the 4 EEG leads (A+,A-,B+,B-), with respect to the Common Neck Reference. During each session, 2 electrodes (A- and B-) are attached to the participant's left and right mastoids, while the remaining two electrodes (A+ and B+) are moved to various locations on the scale to record EEG signals. All four (A+,A-,B+,B-) electrodes are involved in applying weak electrical pulses back to the brain (feedback process). The brief feedback pulse (\~100mV) is adaptive and determined based on the offset of the frequency spectrum recorded across the left and right hemisphere (A vs. B) electrodes in the time window immediately prior to stimulation.

Trial Locations (1)

02130-4817

RECRUITING

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston

All Listed Sponsors
lead

VA Office of Research and Development

FED