NCT06105918View on ClinicalTrials.gov

Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients with Biochemically Recurrent Prostate Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

November 29, 2023

Primary Completion Date

April 1, 2028

Study Completion Date

April 1, 2029

Conditions
Biochemically Recurrent Prostate CarcinomaProstate Adenocarcinoma
Interventions
PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Computed Tomography

Undergo rhPSMA-7.3 PET/CT and SPECT-CT

RADIATION

External Beam Radiation Therapy

Undergo EBRT

OTHER

Flotufolastat F-18

Given IV

DRUG

Lutetium Lu 177 PSMA-10.1

Given IV

PROCEDURE

Positron Emission Tomography

Undergo rhPSMA-7.3 PET/CT

PROCEDURE

Single Photon Emission Computed Tomography

Undergo SPECT-CT scan

Trial Locations (1)

30322

RECRUITING

Emory University Hospital/Winship Cancer Institute, Atlanta

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Emory University

OTHER