MSCs for the Treatment of Burn Wounds

PHASE1/PHASE2Enrolling by invitationINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 30, 2021

Primary Completion Date

June 30, 2023

Study Completion Date

June 30, 2025

Conditions
Burn WoundSecond- or Third-degree Burn
Interventions
BIOLOGICAL

Implantation of allogeneic MSCs on burn wounds

Transplantation of allogeneic MSCs in patients with deep- or full-thickness burns. Allogeneic MSCs embedded in autologous platelet rich plasma clot (PRP) are implanted onto the burned areas. The treated areas will be covered with conventional dressings and burned roll. Dressings will be changed after 5 days and then weekly. The total number of MSCs used in each patient varied according to the burn injury. In patients with larger burned areas, its necessary to apply new treatments with MSCs in affected areas, at intervals of at least 1 month. Implantation will be performed in the operating room. Patients will receive first line treatments.

Trial Locations (1)

1204

Instituto Venezolano de Investigaciones Cientificas, Caracas

All Listed Sponsors
collaborator

Unidad de Terapia Celular - IVIC

UNKNOWN

collaborator

Hospital Pediátrico Niño Jesús, San Felipe, Yaracuy

UNKNOWN

collaborator

Hospital Central Dr. Plácido D. Rodriguez Rivero, San Felipe, Yaracuy

UNKNOWN

lead

Instituto Venezolano de Investigaciones Cientificas

OTHER