Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) for Prevention of HIV in People Who Inject Drugs (HPTN 103)

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

181

Participants

Timeline

Start Date

December 13, 2023

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2028

Conditions
Pre-Exposure Prophylaxis of HIV Infection
Interventions
DRUG

Lenacapavir Injection

Administered subcutaneously

DRUG

Lenacapavir Tablet

Administered orally

DRUG

Emtricitabine/tenofovir disoproxil fumarate (F/TDF)

Administered orally

Trial Locations (9)

10451

ICAP at Columbia University- Bronx Prevention Center, The Bronx

19104

University of Pennsylvania, Division of Infectious Diseases Penn Prevention Research Unit, Philadelphia

21287

Johns Hopkins Medicine Institute for Clinical and Translational Research, Clinical Research, Baltimore

26506

West Virginia University, Morgantown

33136

University of Miami - Converge Miami Building, Miami

77030

Houston AIDS Research Team CRS, Houston

90038

UCLA Vine Street Clinic, Los Angeles

92103

UCSD AntiViral Research Center (AVRC), San Diego

07103

Rutgers New Jersey Medical School, Department of Medicine, Newark

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

HIV Prevention Trials Network

NETWORK

collaborator

National Institute on Drug Abuse (NIDA)

NIH

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Gilead Sciences

INDUSTRY