Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

October 30, 2023

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Keratoconus
Interventions
COMBINATION_PRODUCT

Riboflavin and Sodium Iodide solution and Ultraviolet-A treatment

"Drug: Ribostat riboflavin and sodium iodide ophthalmic solution~Device: UV-3000 ultraviolet A light source"

COMBINATION_PRODUCT

Placebo and sham treatment

"Drug: placebo ophthalmic solution~Device: UV-3000 light source"

Trial Locations (13)

13057

The Eye Doctors at CNY Eye Care, East Syracuse

15219

UPMC Vision Institute, Pittsburgh

19107

Wills Eye Hospital, Philadelphia

22903

University of Virginia, Charlottesville

33176

Center for Excellence in Eye Care, Miami

45219

Cincinnati Eye Institute, Cincinnati

60169

Chicago Cornea Consultants, Hoffman Estates

63131

Ophthalmology Associates, St Louis

77030

Baylor College of Medicine, Houston

91748

Nvision Eye Centers Rowland Heights, Rowland Heights

94115

Goodman Eye Center, San Francisco

97210

Devers Eye Institute, Portland

02445

Boston Vision, Brookline

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Epion Therapeutics

INDUSTRY