20
Participants
Start Date
October 29, 2024
Primary Completion Date
November 30, 2025
Study Completion Date
December 31, 2025
Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN)
This method of simultaneous vagal and trigeminal stimulation via the external ear is known as transcutaneous auricular neurostimulation (tAN), as the targets of electrical stimulation include the auricular branch of the vagus nerve (ABVN) and auriculotemporal nerve (ATN), which is a branch of the mandibular division of the trigeminal nerve. Electrodes applied to select dermatome regions can target ear neural structures and deliver non-invasive vagus nerve stimulation (VNS) and trigeminal nerve stimulation (TNS). Use of tAN for pain relief is an attractive alternative to pharmacologic and opioid-based approaches because it is safe and effective and presents no addiction liability.
Sham Control Device
This device looks like the active device, but no stimulation will be delivered.
RECRUITING
UT Southwestern Medical Center, Dallas
University of Texas Southwestern Medical Center
OTHER