500
Participants
Start Date
September 22, 2015
Primary Completion Date
September 22, 2025
Study Completion Date
September 22, 2026
Plasma Test
IGF-2 (insulin-like growth factor 2)
Plasma test
SPARC (secreted protein acidic and rich in cysteine)
Plasma test
EPICAN (heparan sulfate proteoglycan)
Plasma test
EGFR (epidermal growth factor receptor)
Liver biopsy
Fibrosis and steatosis grade according to Brunt-Kleiner classification
Visceral adipose tissue biopsy
Presence of inflammation
Liver elastography
Grade of fibrosis according to Hamaguchi score
Blood test
Determination of surrogate based diagnostic tests/scores for liver fibrosis
RECRUITING
Silvia Palmisano, Trieste
University of Trieste
OTHER