Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 5, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

January 31, 2039

Conditions
Light Chain (AL) Amyloidosis
Interventions
BIOLOGICAL

NXC-201 CAR-T

NXC-201 (formerly HBI0101) CAR-T is defined as autologous T cells transduced ex-vivo with anti-BCMA CAR retroviral vector encoding the chimeric antigen receptor (CAR) targeted to human BCMA. The NXC-201 CAR-T is provided fresh without cryopreservation.

Trial Locations (18)

10065

RECRUITING

Memorial Sloan Kettering Comprehensive Cancer Center, New York

30322

RECRUITING

Winship Cancer Institute, Emory University, Atlanta

44195

RECRUITING

Cleveland Clinic, Cleveland

45267

RECRUITING

University of Cincinnati Cancer Center, Cincinnati

48201

RECRUITING

Barbara Ann Karmanos Cancer Institute, Detroit

55455

RECRUITING

Masonic Cancer Center, University of Minnesota, Minneapolis

63110

RECRUITING

Washington University Siteman Cancer Center, St Louis

66205

RECRUITING

The University of Kansas Cancer Center, Fairway

84112

RECRUITING

Huntsman Cancer Institute at the University of Utah, Salt Lake City

90095

RECRUITING

University of California Los Angeles, Los Angeles

91010

RECRUITING

City of Hope, Duarte

94305

RECRUITING

Stanford University, Stanford

94704

RECRUITING

Sutter Health Alta Bates, Berkeley

95817

RECRUITING

University of California Davis Medical Center, Sacramento

98104

RECRUITING

Swedish Cancer Institute, Seattle

381202127

RECRUITING

Baptist Memorial Hospital, Memphis

02111

RECRUITING

Tufts Medical Center, Boston

02118

RECRUITING

Boston University Medical Center, Boston

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Immix Biopharma, Inc.

INDUSTRY

lead

Nexcella Inc.

INDUSTRY