Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population

NANot yet recruitingINTERVENTIONAL
Enrollment

3,684

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

November 1, 2025

Study Completion Date

November 1, 2027

Conditions
Acute Coronary SyndromeNon ST Segment Elevation Acute Coronary Syndrome
Interventions
DRUG

Tafolecimab

The PCSK9 mAb in this study is defined as Tafolecimab 150mg q2w subcutaneously. For the two groups of lipid-lowering regimens, the lipid-lowering drug regimens other than PCSK9 mAb were maintained throughout the study as much as possible in accordance with the guidelines related to blood lipids, provided that no serious safety problems occurred.

DRUG

Cholesterol Absorption Inhibitor

Cholesterol absorption inhibitors (like Ezetimibe and Hybutimibe) are based on physician decisions, but need to be routinely dosed. Examples of Medications that Meet Study Requirements: Ezetimibe 10mg Po qd.

DRUG

Statin

Statin are based on physician decisions, but need to be routinely dosed. Examples of Medications that Meet Study Requirements: Atorvastatin 20mg Po qn, Rosuvastatin 10mg Po qn or Pitavastatin 4mg Po qn.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Innovent Biologics, Inc.

OTHER

lead

China National Center for Cardiovascular Diseases

OTHER_GOV

NCT06096909 - Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population | Biotech Hunter | Biotech Hunter