55
Participants
Start Date
May 29, 2024
Primary Completion Date
July 31, 2025
Study Completion Date
December 31, 2025
robotic assisted intervention
Robotic treatment of the upper limb (30 sessions, 5 times a week) using a set of 4 robotic devices: Motore (Humanware); Amadeo, Diego, Pablo (Tyromotion). The training will include motor-cognitive exercises specifically selected to train spatial attention, vision and working memory, praxis, executive function, and speed of processing.
hematochemical analysis
Blood samples of patients will be collected from patients in the early morning (7:30-9:00 a.m.) after an overnight fast at T0 and at T1. Sera samples will be separated by centrifugation (3,000 rpm, 10 min, and 4 °C), divided into 0.5 mL aliquots, and rapidly stored at -80 °C. Subjects' and reference samples were thawed just before the diagnostic test.
BIA, hand grip
bioimpedentiometric analyses of muscular mass (T0 and T1), muscular force with hand grip
nutritional assessment, MNA,
nutritional status assessment will be performed by: body mass index measurements, (height and weight measurements at T0 and at T1); a Mini Nutritional Assessment survey will be administered to patients at admission; a food questionnaire will be administered to patients during from T0 to T1.
stool sampling
stool will be collected at T0 and at T1
urine sampling
the first morning urine will be collected at T0 and at T1
indirect calorimetry analysis
indirect calorimetry analysis with K5 (COSMED, Italy) during six minute walk test or timed up and go test.
RECRUITING
Fondazione Don Carlo Gnocchi, Santa Maria della Provvidenza Center, Roma
Fondazione Don Carlo Gnocchi Onlus
OTHER