Nutritional Status in Subacute Stroke Patients Under Rehabilitation 2.0

RecruitingOBSERVATIONAL
Enrollment

55

Participants

Timeline

Start Date

May 29, 2024

Primary Completion Date

July 31, 2025

Study Completion Date

December 31, 2025

Conditions
Stroke
Interventions
DEVICE

robotic assisted intervention

Robotic treatment of the upper limb (30 sessions, 5 times a week) using a set of 4 robotic devices: Motore (Humanware); Amadeo, Diego, Pablo (Tyromotion). The training will include motor-cognitive exercises specifically selected to train spatial attention, vision and working memory, praxis, executive function, and speed of processing.

DIAGNOSTIC_TEST

hematochemical analysis

Blood samples of patients will be collected from patients in the early morning (7:30-9:00 a.m.) after an overnight fast at T0 and at T1. Sera samples will be separated by centrifugation (3,000 rpm, 10 min, and 4 °C), divided into 0.5 mL aliquots, and rapidly stored at -80 °C. Subjects' and reference samples were thawed just before the diagnostic test.

DEVICE

BIA, hand grip

bioimpedentiometric analyses of muscular mass (T0 and T1), muscular force with hand grip

DIAGNOSTIC_TEST

nutritional assessment, MNA,

nutritional status assessment will be performed by: body mass index measurements, (height and weight measurements at T0 and at T1); a Mini Nutritional Assessment survey will be administered to patients at admission; a food questionnaire will be administered to patients during from T0 to T1.

DIAGNOSTIC_TEST

stool sampling

stool will be collected at T0 and at T1

DIAGNOSTIC_TEST

urine sampling

the first morning urine will be collected at T0 and at T1

DEVICE

indirect calorimetry analysis

indirect calorimetry analysis with K5 (COSMED, Italy) during six minute walk test or timed up and go test.

Trial Locations (1)

00166

RECRUITING

Fondazione Don Carlo Gnocchi, Santa Maria della Provvidenza Center, Roma

All Listed Sponsors
lead

Fondazione Don Carlo Gnocchi Onlus

OTHER