72
Participants
Start Date
October 16, 2023
Primary Completion Date
December 30, 2025
Study Completion Date
June 30, 2026
IV Decitabine
The subjects will receive decitabine 20 mg/m\^2 IV daily × 5 days in 28-day cycles.
Decitabine and cedazuridine
subjects will receive treatment with ASTX727, 1 tablet/day for 5 consecutive days, in 28-day cycles.
only Decitabine and cedazuridine
subjects will receive treatment with ASTX727, 1 tablet/day for 5 consecutive days, in 28-day cycles, until disease progression, unacceptable toxicity, or the subject/investigator decides that the subject should discontinue treatment or withdraw from the trial.
The First Affiliated Hospital,Zhejiang University School of Medicine, Hangzhou
Lead Sponsor
Otsuka Beijing Research Institute
INDUSTRY