Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

December 1, 2027

Study Completion Date

December 31, 2027

Conditions
OSA
Interventions
DRUG

Acetazolamide

Administered for 3 nights, half-dose (1 pill) on the first night followed by full dose (2x250mg pills) for 2 nights

DRUG

Placebo

Placebo sugar pills administered for 3 nights, half-dose (1 pill) on the first night followed by full dose (2 pills) for 2 nights

Trial Locations (1)

02141

RECRUITING

Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER