National Liver Cancer Screening Trial

PHASE4RecruitingINTERVENTIONAL
Enrollment

5,500

Participants

Timeline

Start Date

December 26, 2023

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2034

Conditions
Carcinoma, HepatocellularLiver CancerLiver CirrhosisHepatitis B
Interventions
DIAGNOSTIC_TEST

GALAD

GALAD is a 3 biomarker panel incorporating AFP, AFP-L3% and DCP (all FDA approved), with patient age and sex.

DIAGNOSTIC_TEST

Liver Ultrasound with or without AFP

This intervention consists of current standard of care ultrasound based surveillance with or without alpha-fetoprotein measurement.

Trial Locations (17)

11030

RECRUITING

The Feinstein Institutes, Northwell Health, Inc., Manhasset

19104

RECRUITING

University of Pennsylvania, Philadelphia

23219

NOT_YET_RECRUITING

Virginia Commonwealth University, Richmond

27599

RECRUITING

University of North Carolina, Chapel Hill

46202

RECRUITING

Indiana University, Indianapolis

48109

RECRUITING

University of Michigan, Ann Arbor

48202

RECRUITING

Henry Ford Health System, Detroit

55415

RECRUITING

Hennepin Healthcare, Minneapolis

55455

RECRUITING

University of Minnesota, Minneapolis

60611

RECRUITING

Northwestern University, Chicago

75390

RECRUITING

UT Southwestern Medical Center and Parkland Hospital, Dallas

77021

RECRUITING

Baylor College of Medicine, Houston

90089

RECRUITING

University of Southern California, Los Angeles

94063

RECRUITING

Stanford University, Redwood City

94117

RECRUITING

University of California, San Francisco, San Francisco

95661

RECRUITING

Kaiser Permanente, Roseville

02114

RECRUITING

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

University of Pennsylvania

OTHER

collaborator

University of Michigan

OTHER

collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

Baylor College of Medicine

OTHER

collaborator

Fred Hutchinson Cancer Center

OTHER

lead

University of Texas Southwestern Medical Center

OTHER

NCT06084234 - National Liver Cancer Screening Trial | Biotech Hunter | Biotech Hunter