The Efficacy and Safety of IBI363 in Solid Tumors

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

430

Participants

Timeline

Start Date

December 25, 2023

Primary Completion Date

December 1, 2026

Study Completion Date

September 1, 2028

Conditions
Advanced Solid Tumor
Interventions
DRUG

IBI363

"IBI363 is based on the 3+3 model with a dose of 1 mg/kg Q3W. IBI325, 20 mg/kg Q3W."

DRUG

IBI363

"IBI363 is based on the 3+3 model with a dose of 1.5 mg/kg Q3W. IBI325, 20 mg/kg Q3W."

DRUG

IBI363

"IBI363 is based on the 3+3 model with a dose of 600 μg/kg Q2W. Lenvatinib, 8mg QD."

DRUG

IBI363

"IBI363 is based on the 3+3 model with a dose of 1000 μg/kg Q2W. Lenvatinib, 8mg QD."

DRUG

IBI363

The recommended dosages for IBI363, IBI325, and Lenvatinib in Phase Ib will be determined based on a comprehensive assessment of safety, efficacy, and other data obtained from the safety introduction portions of both Phase Ia (Part A) and Phase Ib (Part B).

Trial Locations (1)

410013

RECRUITING

Yongchang Zhang, Changsha

All Listed Sponsors
collaborator

Xiangya Hospital of Central South University

OTHER

lead

Hunan Province Tumor Hospital

OTHER