Ketogenic Diet vs Mixed Diet in Patients With Heart Failure

NARecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

May 19, 2023

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
DIETARY_SUPPLEMENT

Ketogenic diet

Participants will undertake a controlled feeding intervention. All food will be prepared and delivered to participants by research staff for the first 6 weeks. After that will be a free-living diet period where food will not be supplied but participants will receive educational materials and frequent coaching from a dietitian to help maintain the specified diet. Participants will be asked to exclusively follow the diet in efforts to control any dietary effects.

DIETARY_SUPPLEMENT

Low-fat Mixed diet

Participants will undertake a controlled feeding intervention. All food will be prepared and delivered to participants by research staff for the first 6 weeks. After that will be a free-living diet period where food will not be supplied but participants will receive educational materials and frequent coaching from a dietitian to help maintain the specified diet. Participants will be asked to exclusively follow the diet in efforts to control any dietary effects.

Trial Locations (1)

43210

RECRUITING

The Ross Heart Hospital, Columbus

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Ohio State University

OTHER