80
Participants
Start Date
November 1, 2023
Primary Completion Date
November 1, 2024
Study Completion Date
December 1, 2024
Metformin
The intervention will consist in giving metformin starting with 500 mg once daily 1 gm daily (at breakfast) during the first week; if well tolerated, the dose was progressively increased to 500 mg twice daily (at breakfast and dinner) during week 2, to 1000 mg at breakfast and 500 mg at dinner during week 3, in order to reach the target dose of 1000 mg twice daily (at breakfast and dinner) during the rest of the follow-up. Patients will be followed up by telephone call 2 weeks intervals during the study period 5 SGL-2 will be prescribed to group 1 after diagnosis with HFpEF while group 2 will have SGL-2 and Metformin
clinical research uint- El-sheikh zayed specialized hospital SMC- Egyptian Ministry of health, Cairo
clinical research unit, El-sheikh zayed specialized hospital - Egyptian Ministry of health
UNKNOWN
October University for Modern Sciences and Arts
OTHER