MIST Versus M-MIST for the Treatment of Intrabony Defects

NAActive, not recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

August 10, 2023

Primary Completion Date

January 10, 2025

Study Completion Date

June 10, 2025

Conditions
PeriodontitisIntrabony Periodontal DefectPeriodontitis, Chronic
Interventions
PROCEDURE

M-MIST

This is characterized by a vestibular mucoperiosteal envelope flap without relaxing incisions. Sulcular incisions will be made on the vestibular surface of the teeth included in the surgical area, adjacent to the infraosseous defect. The mesiodistal extension of the flap will be kept to a minimum necessary to access the defect. In the papillary area over the infraosseous defect, an oblique or horizontal incision will be made at the level of the interdental papilla, following the contour of the bone crest. The vestibular flap will be elevated, leaving the lingual/palatal portion adhered, only to allow access to the bone defect. The defect will be instrumented with mini-curettes and specific ultrasonic tips, and the defect will be filled only with a blood clot after this procedure. Primary closure will be achieved with internal vertical and/or horizontal mattress sutures, which may be complemented with simple sutures, all using specific suture threads.

PROCEDURE

MIST

A vestibular envelope flap, without vertical relaxing incisions, will be raised on the vestibular and lingual/palatal sides. Primary intrasulcular incisions will be made to the alveolar crest, encompassing the teeth included in the surgical area. In the interproximal area, incisions will follow the principle of preserving the papilla (Modified Papilla Preservation Technique = MPPT or Simplified Papilla Preservation Flap = SPPF), depending on the available interproximal space (Cortellini et al., 1995, 1999). The mesiodistal extension of the flap will be minimized to provide adequate access to the defect. The defect will be instrumented using mini-curettes and specific ultrasonic tips, and the defect will be filled only with a blood clot after these procedures. Flap closure will be achieved with internal horizontal and/or vertical mattress sutures, which may be modified or complemented with simple sutures, all using specific suture threads.

Trial Locations (1)

13414903

Piracicaba Dental School, State University of Campinas, Piracicaba

All Listed Sponsors
lead

University of Campinas, Brazil

OTHER

NCT06058923 - MIST Versus M-MIST for the Treatment of Intrabony Defects | Biotech Hunter | Biotech Hunter