PET/MRI in Rectal Cancer

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

May 31, 2026

Primary Completion Date

May 31, 2029

Study Completion Date

December 31, 2030

Conditions
Rectal Cancer
Interventions
RADIATION

Total Neo-adjuvant Therapy

"* TNT incorporates chemotherapy with concurrent chemoradiotherapy (CRT) in any order.~* Radiotherapy includes 5000 cGy/25 fractions over 5 weeks.~* Chemotherapy regimen for Concurrent CRT: Capecitabine~* Chemotherapy regimens used with TNT are: FOLFIRINOX x 6 cycles, 8-9 courses FOLFOX or 5-6 courses of CAPEOX delivered over 4-6 months.~* The chemotherapy regimen or the order of treatment will be decided at the discretion of the patient's medical oncologist"

OTHER

18FDG-PET/MRI scan

18FDG-PET/MRI scan within 4 weeks of commencing chemo-radiation and within 1 - 2 weeks before radical rectal cancer surgery.

All Listed Sponsors
lead

AHS Cancer Control Alberta

OTHER