Post Marketing Surveillance of Diphtheria Antitoxin (DAT)

"Dosage form: Solution for injection~Dosage:~1. Perform sensitivity tests, and desensitization if necessary.~2. Give the entire treatment dose of antitoxin IV (or IM) in a single administration (except for series of injections needed for desensitization).~3. The recommended DAT treatment dosage ranges (pediatric and adult) are:~ * Pharyngeal or laryngeal disease of 2 days duration 20,000 - 40,000 unit~ * Nasopharyngeal disease 40,000 - 60,000 unit~ * Extensive disease of 3 or more days duration, or any patient with diffuse swelling of neck 80,000 - 100,000 unit~ * Skin lesions only (rare case where treatment is indicated) 20,000 - 40,000 unit"