Spatial-Motor Stroke-Rehab Study

NARecruitingINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

April 11, 2023

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Spatial NeglectStroke
Interventions
DEVICE

Prism adaptation therapy (PAT) + Electrical stimulation (E-stim)

PAT requires one to wear prism lenses while making arm-reaching movements toward visual targets. For treating left-sided neglect, a person wears the prism lenses that shift the visual field, including the images of the target and of one's own reaching arm, certain degrees to the right depending on the diopter of the lens (e.g., the 20-diopter lens shifts the visual field by 11.4 degrees). The visual system adapts over the repetitive practice of the arm reaching toward the target. The person eventually achieves success with a leftward movement reaching the actual target. Electrical stimulation (E-stim) involves parameters and settings commonly used in clinical practice as well as research for pain relief and other applications, commonly referred to as transcutaneous electrical nerve stimulation (TENS). TENS and E-stim are delivered using FDA-approved, commercially available portable clinical transcutaneous electrical stimulators (e.g. Empi TENS Unit).

DEVICE

Prism adaptation therapy (PAT) + Sham Stimulator

Participants in the PAT with sham stim condition group will receive sham electrical stimulation treatment (electrodes will be attached but the stimulator will not be turned on) to the left upper limb with the same placement of electrodes while undergoing PAT.

OTHER

Gait Training

After PAT, participants will complete multiple 30-seconds to 4-minute bouts of walking on the treadmill or overground at speeds ranging from self-selected to fast speeds (faster than comfortable self-selected speed), with rest breaks between bouts.

Trial Locations (3)

30322

RECRUITING

Emory Rehabilitation Hospital, Atlanta

RECRUITING

Emory University Hospital (EUH), Atlanta

30329

RECRUITING

Executive Park, Atlanta

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Emory University

OTHER