65
Participants
Start Date
April 11, 2023
Primary Completion Date
March 31, 2026
Study Completion Date
March 31, 2026
Prism adaptation therapy (PAT) + Electrical stimulation (E-stim)
PAT requires one to wear prism lenses while making arm-reaching movements toward visual targets. For treating left-sided neglect, a person wears the prism lenses that shift the visual field, including the images of the target and of one's own reaching arm, certain degrees to the right depending on the diopter of the lens (e.g., the 20-diopter lens shifts the visual field by 11.4 degrees). The visual system adapts over the repetitive practice of the arm reaching toward the target. The person eventually achieves success with a leftward movement reaching the actual target. Electrical stimulation (E-stim) involves parameters and settings commonly used in clinical practice as well as research for pain relief and other applications, commonly referred to as transcutaneous electrical nerve stimulation (TENS). TENS and E-stim are delivered using FDA-approved, commercially available portable clinical transcutaneous electrical stimulators (e.g. Empi TENS Unit).
Prism adaptation therapy (PAT) + Sham Stimulator
Participants in the PAT with sham stim condition group will receive sham electrical stimulation treatment (electrodes will be attached but the stimulator will not be turned on) to the left upper limb with the same placement of electrodes while undergoing PAT.
Gait Training
After PAT, participants will complete multiple 30-seconds to 4-minute bouts of walking on the treadmill or overground at speeds ranging from self-selected to fast speeds (faster than comfortable self-selected speed), with rest breaks between bouts.
RECRUITING
Emory Rehabilitation Hospital, Atlanta
RECRUITING
Emory University Hospital (EUH), Atlanta
RECRUITING
Executive Park, Atlanta
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Emory University
OTHER