18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery

PHASE1RecruitingINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

April 11, 2024

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2027

Conditions
Brain MetastasesBrain Metastases, AdultBrain Cancer
Interventions
DRUG

18F fluciclovine

Participants will receive 5-mCi dose (± 20%) of 18F-fluciclovine intravenously as a bolus injection immediately prior to PET data acquisition. PET data will be collected in list mode up to 25 minutes post-injection. PET images will be reconstructed in two ways: as a standard static image of data acquired between 10 to 20 minutes post-injection, and as a dynamic series of four 5-minute frames between 5 to 25 minutes post-injection to allow for motion assessment and correction and time-dependent observations.

Trial Locations (1)

33176

RECRUITING

Miami Cancer Institute, Miami

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Blue Earth Diagnostics

INDUSTRY

lead

Baptist Health South Florida

OTHER