Dietary Acid Reduction and Progression of Chronic Kidney Disease

NACompletedINTERVENTIONAL
Enrollment

153

Participants

Timeline

Start Date

June 24, 1996

Primary Completion Date

November 15, 2006

Study Completion Date

December 15, 2011

Conditions
Chronic Kidney DiseasesCardiovascular DiseasesHypertension
Interventions
OTHER

Fruits and vegetables (F+V)

Participants will receive a prescribed amount of F+V designed to reduce their dietary acid intake by half. This typically amounts to 2-4 cups/day for each participant randomized to this group, depending on the type of F+Vs used, provided in weekly allotments. Participants will receive standard care for their medical concerns.

DRUG

NaHCO3 Tablets

Participants will receive 0.4 mEq/kg bw NaHCO3 /day, an amount designed to match the alkali provided by the added F+V. This will be provided as 650 mg NaHCO3 tablets for an average of 4-5 tablets/day in 2 divided doses for each participant randomized to this group. Participants will receive standard care for their medical concerns.

OTHER

Usual Care

Participants will receive standard care for their medical concerns and no additional alkali (F+V or NaHCO3).

All Listed Sponsors
lead

University of Texas at Austin

OTHER

NCT06046924 - Dietary Acid Reduction and Progression of Chronic Kidney Disease | Biotech Hunter | Biotech Hunter