EEG Microstates Across At-Risk Mental States

NARecruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

May 30, 2023

Primary Completion Date

July 30, 2026

Study Completion Date

July 30, 2026

Conditions
Psychotic DisordersAutism Spectrum DisorderMajor Depressive DisorderSchizophrenia
Interventions
DEVICE

EEG 64 channels

64-channel EEG in wake and resting conditions for 1h30, with oculogram, electromyogram and electromyogram and electrocardiogram. Five minutes of eyes closed will be used for microstate analysis. 1h30 will be used for the sensorimotor task.

DEVICE

Polysomnography 19 electrodes

Overnight polysomnography with 19 EEG channels and ventilatory polygraphy.

BEHAVIORAL

Light hypnosis

Healthy controls will undergo a 5 min light hypnosis exercise that will be focused on proprioception.

BIOLOGICAL

Biological sampling

Blood samples will be taken for genetic, epigenetic, proteomic, and metabolomic studies.

BEHAVIORAL

Virtual reality

Participants will undergo a virtual reality task using a head-mounted display, and their multidimensional self will be assessed prior to and after the task via the self-reference effect on episodic memory.

DEVICE

Voice recording

A double channel audio recorder will be used during 30 min to assess voice characteristics of all subjects.

Trial Locations (1)

75014

RECRUITING

Centre de Recherche Clinique, Hôpital Sainte-Anne, GHU Paris Psychiatrie et Neurosciences, Paris

All Listed Sponsors
collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

lead

Centre Hospitalier St Anne

OTHER