NCT06044935View on ClinicalTrials.gov

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 8, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2028

Conditions
OverweightObesity
Interventions
OTHER

Standard Diet

Consisting of 15% protein, 35% fat, and 50% carbohydrate, matching the macronutrient composition of a typical American diet

OTHER

Ketogenic Diet

Consisting of a macronutrient composition of 15% protein, 80% fat, and 5% carbohydrate

DIETARY_SUPPLEMENT

Placebo

Subjects without MODY2 will take either placebo or NR (1 g BID, 2 g per day total) supplements for 7 days during this Run-in phase

DIETARY_SUPPLEMENT

Nicotinamide Riboside

Subjects without MODY2 will take either placebo or NR (1 g BID, 2 g per day total) supplements for 7 days during this Run-in phase

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH