60
Participants
Start Date
January 17, 2024
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Sevoflurane
After a no-drug control period, subjects will inhale sevoflurane, administered via a breathing circuit and face mask, until a steady-state target end-tidal expired concentration of 0.4% (corresponding to 0.2 Minimum Alveolar Concentration) is reached.
Peripheral Nerve Stimulation
Experimental acute pain stimulus will be delivered using a nerve stimulator. These painful shocks will be paired with a fixed number of the experimental cues, in a pattern that appears random to participants.
RECRUITING
University of Pittsburgh, Pittsburgh
National Institute of General Medical Sciences (NIGMS)
NIH
Keith M Vogt
OTHER