A Study to Assess the Safety, Tolerability and Preliminary Efficacy of HH-120 for the Treatment of COVID-19

PHASE1CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

April 16, 2022

Primary Completion Date

October 10, 2022

Study Completion Date

October 10, 2022

Conditions
COVID-19
Interventions
DRUG

HH-120

Participants randomized to active treatment in escalation phase will receive HH-120 administered via inhalation for 5 consecutive days (Day 1 to Day 5). Planned dose levels to be used for the escalation phase of the study are 50 (BID), 50 (TID), and 100 (BID) mg. The expansion phase will begin once the recommended dose for expansion phase determined, based on safety and preliminary efficacy data from the escalation phase.

DRUG

placebo

Participants randomized to placebo group in escalation and expansion phase will receive placebo administered via inhalation for 5 consecutive days (Day 1 to Day 5).

Trial Locations (4)

100015

Beijing Ditan Hospital,Capital Medical University, Beijing

130021

The First Hospital of Jilin University, Changchun

200040

Huashan Hospital affiliated to Fudan University, Shanghai

510440

Guangzhou Eighth People's,Guangzhou Medical University, Guangzhou

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Huahui Health

INDUSTRY

NCT06039163 - A Study to Assess the Safety, Tolerability and Preliminary Efficacy of HH-120 for the Treatment of COVID-19 | Biotech Hunter | Biotech Hunter