30
Participants
Start Date
April 15, 2024
Primary Completion Date
November 30, 2025
Study Completion Date
November 30, 2025
Adalimumab
Participants will be randomized 1:1 (non-blinded) to receive either adalimumab (40 mg subcutaneous every 2 weeks for 12 weeks) and prednisone vs prednisone alone. Addition of methotrexate (MTX) and/or hydroxychloroquine (HCQ) is permitted, as needed, at the discretion of the treating rheumatologist. No additional conventional synthetic, targeted synthetic or biologic DMARDs are permitted during the trial.
Prednisone
Prednisone as per standard of care.
RECRUITING
St. Joseph's Health Care, London
Canadian Research Group in Immuno-Oncology
UNKNOWN
Western University
OTHER
Tom Appleton
OTHER