The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics

RecruitingOBSERVATIONAL
Enrollment

25

Participants

Timeline

Start Date

July 22, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Compartment Syndrome Nontraumatic Lower Extremity
Interventions
DEVICE

NIRS monitoring

All participants will undergo NIRS monitoring of muscle and cerebral tissue oxygenation intraoperatively.

DEVICE

Laser Doppler flowmetry

Cutaneous blood flow will be assessed intraoperatively via Laser Doppler flowmetry in all participants

OTHER

Inflammatory and Oxidative stress biomarkers

Blood samples will be taken to measure biomarkers of inflammation and oxidative stress at specific time points

Trial Locations (1)

PO6 3LY

RECRUITING

Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust, Portsmouth

All Listed Sponsors
collaborator

Portsmouth Hospitals NHS Trust

OTHER_GOV

lead

University of Portsmouth

OTHER