A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

PHASE1RecruitingINTERVENTIONAL
Enrollment

230

Participants

Timeline

Start Date

December 4, 2023

Primary Completion Date

October 29, 2028

Study Completion Date

October 29, 2028

Conditions
Myeloproliferative Neoplasms
Interventions
DRUG

INCA033989

INCA033989 will be administered at protocol defined dose.

DRUG

Ruxolitinib

Rux will be administered according to Prescribing Information/SmPC.

Trial Locations (13)

10029

RECRUITING

Icahn School of Medicine At Mount Sinai, New York

10065

RECRUITING

Memorial Sloan Kettering Cancer Center, New York

21287

RECRUITING

Johns Hopkins Hospital, Baltimore

27157

RECRUITING

Wake Forest Baptist Medical Center, Winston-Salem

33136

RECRUITING

University of Miami Health System, Miami

37232

RECRUITING

Vanderbilt University Medical Center, Nashville

44195

RECRUITING

Cleveland Clinic, Cleveland

63108

RECRUITING

Washington University School of Medicine, St Louis

66205

RECRUITING

The University of Kansas Cancer Center, Westwood

77030

RECRUITING

Md Anderson Cancer Center, Houston

91010

RECRUITING

City of Hope Medical Center, Duarte

94304

RECRUITING

Stanford Cancer Institute, Palo Alto

02215

RECRUITING

Dana Farber Cancer Institute, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Incyte Corporation

INDUSTRY