Ketone Dose and Cerebral Blood Flow Study

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

November 8, 2023

Primary Completion Date

May 31, 2024

Study Completion Date

August 31, 2024

Conditions
Cerebrovascular FunctionCognition
Interventions
DIETARY_SUPPLEMENT

Low Dose β-OHB

Ingestion of a low dose \[R\]-3-hydroxybutyl \[R\]-3-hydroxybutyrate (0.3 g β-OHB/kg body weight) followed by 2-hours of rest. Submaximal exercise to be performed following 2-hour resting measures.

DIETARY_SUPPLEMENT

High Dose β-OHB

Ingestion of a high dose \[R\]-3-hydroxybutyl \[R\]-3-hydroxybutyrate (0.6 g β-OHB/kg body weight) followed by 2-hours of rest. Submaximal exercise to be performed following 2-hour resting measures.

OTHER

Placebo

Ingestion of a taste-matched calorie-free placebo drink followed by 2-hours of rest. Submaximal exercise to be performed following 2-hour resting measures.

Trial Locations (1)

L8S 4K1

RECRUITING

McMaster University, Hamilton

All Listed Sponsors
lead

McMaster University

OTHER